Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice

Leukocyte CD11b expression is not essential for the development of atherosclerosis in mice

CD11b is an α chain of the leukocyte β2-integrin, Mac-1, which mediates binding and extravasation of leukocytes. Because this event is critical in atherosclerosis, we examined the role of CD11b in lesion formation. Atherosclerosis-susceptible, low density lipoprotein receptor-deficient (LDL-R−/−) mi...

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Bibliographic Details
Main Authors:	Nobuhiko Kubo, William A. Boisvert, Christie M. Ballantyne, Linda K. Curtiss
Format:	Article
Language:	English
Published:	Elsevier 2000-07-01
Series:	Journal of Lipid Research
Subjects:	transgenic/knockout fluorescence-activated cell sorting in vivo animal models adhesion molecules inflammation
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520320101

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