Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

<p>Abstract</p> <p>Background</p> <p>Next-generation DNA sequencing is opening new avenues for genetic association studies in common diseases that, like deep vein thrombosis (DVT), have a strong genetic predisposition still largely unexplained by currently identified ri...

Full description

Bibliographic Details
Main Authors: Lotta Luca A, Wang Mark, Yu Jin, Martinelli Ida, Yu Fuli, Passamonti Serena M, Consonni Dario, Pappalardo Emanuela, Menegatti Marzia, Scherer Steven E, Lewis Lora L, Akbar Humeira, Wu Yuanqing, Bainbridge Matthew N, Muzny Donna M, Mannucci Pier M, Gibbs Richard A, Peyvandi Flora
Format: Article
Language:English
Published: BMC 2012-02-01
Series:BMC Medical Genomics
Subjects:
Deep vein thrombosis
venous thromboembolism
next-generation sequencing
target capture
multiplexing
FGA
rs6025
heamostateome
DVT
VTE
Online Access:http://www.biomedcentral.com/1755-8794/5/7

Internet

http://www.biomedcentral.com/1755-8794/5/7

Similar Items