In-silico molecular designs to treat neurologic and ophthalmologic diseases caused by sorbitol excess: engineering the Agrobacterium vitis protein

In-silico molecular designs to treat neurologic and ophthalmologic diseases caused by sorbitol excess: engineering the Agrobacterium vitis protein

Abstract This work presents the design of a new protein based on the adenosine triphosphate-binding cassette (ABC) transporter solute binding protein (SBP) derived from Agrobacterium vitis, a gram-negative plant pathogen. The Protein Data Bank in Europe’s dictionary of chemical components was utiliz...

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Bibliographic Details
Main Authors: Shonit Nair Sharma, Ashkhan Hojati, Bhargavee Gnanasambandam, Rahul S. Yerrabelli, Joshua Brozek
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Research Notes
Subjects:
Biologic
Protein Engineering
PyRosetta
Cataract
Neuropathy
Online Access:https://doi.org/10.1186/s13104-023-06367-2

Internet

https://doi.org/10.1186/s13104-023-06367-2

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