A feedback loop between lncRNA MALAT1 and DNMT1 promotes triple-negative breast cancer stemness and tumorigenesis

A feedback loop between lncRNA MALAT1 and DNMT1 promotes triple-negative breast cancer stemness and tumorigenesis

Background The function of long non-coding RNA (lncRNA) MALAT1 in regulating triple-negative breast cancer (TNBC) stemness and tumorigenesis was investigated. Methods Sphere formation and colony formation assays coupled with flow cytometry were employed to evaluate the percentage of CD44high/CD44low...

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Bibliographic Details
Main Authors: Yu Hu, Yuqiong He, Na Luo, Xin Li, Lei Guo, Kejing Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Cancer Biology & Therapy
Subjects:
malat1
mir-137
bcl11a
dnmt1
triple-negative breast cancer
cell stemness
positive feedback loop
Online Access:http://dx.doi.org/10.1080/15384047.2023.2235768

Internet

http://dx.doi.org/10.1080/15384047.2023.2235768

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