Combined TLR-3/TLR-8 Signaling in the Presence of α-Type-1 Cytokines Represents a Novel and Potent Dendritic Cell Type-1, Anti-Cancer Maturation Protocol

Combined TLR-3/TLR-8 Signaling in the Presence of α-Type-1 Cytokines Represents a Novel and Potent Dendritic Cell Type-1, Anti-Cancer Maturation Protocol

During the ex vivo generation of anti-cancer dendritic cell (DC)-based vaccines, their maturation still represents one of the most crucial steps of the manufacturing process. A superior DC vaccine should: possess extensive expression of co-stimulatory molecules, have an exceptional type-1 polarizati...

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Bibliographic Details
Main Authors: Tadej Fevžer, Primož Poženel, Kaja Zajc, Nataša Tešić, Urban Švajger
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
dendritic cells
maturation
type-1 polarization
cytotoxic T cells
Online Access:https://www.mdpi.com/2073-4409/11/5/835

Internet

https://www.mdpi.com/2073-4409/11/5/835

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