Safety and audiological outcome in a case series of tertiary therapy of sudden hearing loss with a biodegradable drug delivery implant for controlled release of dexamethasone to the inner ear

Safety and audiological outcome in a case series of tertiary therapy of sudden hearing loss with a biodegradable drug delivery implant for controlled release of dexamethasone to the inner ear

BackgroundIntratympanic injections of glucocorticoids have become increasingly common in the treatment of idiopathic sudden sensorineural hearing loss (ISSHL). However, due to their fast elimination, sustained applications have been suggested for local drug delivery to the inner ear.Materials and me...

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Bibliographic Details
Main Authors: Stefan K. Plontke, Arne Liebau, Eric Lehner, Daniel Bethmann, Karsten Mäder, Torsten Rahne
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neuroscience
Subjects:
glucocorticoids
intracochlear
biodegradable polymer
intratympanic
human
salvage therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.892777/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.892777/full

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