Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

Objectives: Degeneration of the cholinergic basal forebrain nuclei (CBFN) system has been studied extensively in Alzheimer's disease (AD). White matter hyperintensities are a hallmark of aging as well as a common co-morbidity of AD, but their contribution to CBFN degeneration has remained uncle...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Christine Kindler, Neeraj Upadhyay, Zeynep Bendella, Franziska Dorn, Vera C. Keil, Gabor C. Petzold
Format: Artykuł
Język:English
Wydane: Elsevier 2023-01-01
Seria:NeuroImage: Clinical
Hasła przedmiotowe:
Alzheimer's disease
Cerebral small-vessel disease
Cholinergic basal forebrain nucleus
Nucleus basalis of Meynert
White matter hyperintensities
Voxel-based morphometry
Dostęp online:http://www.sciencedirect.com/science/article/pii/S2213158223001687

Internet

http://www.sciencedirect.com/science/article/pii/S2213158223001687

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