Embers of the Past: Early Childhood Traumas Interact with Variation in <i>P2RX7</i> Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk

Embers of the Past: Early Childhood Traumas Interact with Variation in <i>P2RX7</i> Gene Implicated in Neuroinflammation on Markers of Current Suicide Risk

Both early childhood traumatic experiences and current stress increase the risk of suicidal behaviour, in which immune activation might play a role. Previous research suggests an association between mood disorders and <i>P2RX7</i> gene encoding P2X7 receptors, which stimulate neuroinflam...

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Bibliographic Details
Main Authors: Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Beata Sperlagh, Ian M. Anderson, Bill Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
<i>P2RX7</i>
suicide
stress
recent life events
childhood adversities
GxE interaction
Online Access:https://www.mdpi.com/1422-0067/25/2/865

Internet

https://www.mdpi.com/1422-0067/25/2/865

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