Clinical Characteristics, In Silico Analysis, and Intervention of Neonatal-Onset Inflammatory Bowel Disease With Combined Immunodeficiency Caused by Novel TTC7A Variants

Clinical Characteristics, In Silico Analysis, and Intervention of Neonatal-Onset Inflammatory Bowel Disease With Combined Immunodeficiency Caused by Novel TTC7A Variants

We aimed to explore the genotypic and phenotypic characteristics of neonatal-onset inflammatory bowel disease (IBD) with combined immunodeficiency due to TTC7A mutation. We examined the clinical manifestations, imaging results, endoscopic and histological findings, interventions, and prognosis of a...

Full description

Bibliographic Details
Main Authors: Yun-e Chen, Jingfang Chen, Wenxing Guo, Yanhong Zhang, Jialing Li, Hui Xie, Tong Shen, Yunsheng Ge, Yanru Huang, Wenying Zheng, Mei Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
inflammatory bowel disease
immunodeficiency
neonatal
TTC7A
intervention
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.921808/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.921808/full

Similar Items