Anti-Inflammatory Effects of the LK5 Herbal Complex on LPS- and IL-4/IL-13-Stimulated HaCaT Cells and a DNCB-Induced Animal Model of Atopic Dermatitis in BALB/c Mice

Anti-Inflammatory Effects of the LK5 Herbal Complex on LPS- and IL-4/IL-13-Stimulated HaCaT Cells and a DNCB-Induced Animal Model of Atopic Dermatitis in BALB/c Mice

Atopic dermatitis (AD) is a chronic inflammatory skin disease influenced by a complex interplay of genetic and environmental factors. The activation of the JAK-STAT pathway increases the expression of inflammatory cytokines such as IL-4 and IL-13, further deteriorating AD. Therefore, for the treatme...

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Bibliographic Details
Main Authors: Hyun-Jeong Kim, So-Yeon Kim, Ho Jung Bae, Yu-Yeong Choi, Ju-Yeon An, Ye Eun Cho, So-Young Cho, Su-Jung Lee, Sanghyun Lee, MinSub Sin, Young Min Yun, Jong Ryul Lee, Se Jin Park
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceutics
Subjects:
LK5 herbal complex
atopic dermatitis
signal transducers and activators of transcription
itching
anti-inflammation
Online Access:https://www.mdpi.com/1999-4923/16/1/40

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https://www.mdpi.com/1999-4923/16/1/40

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