Premorbid Alterations of Spontaneous Brain Activity in Elderly Patients With Early Post-operative Cognitive Dysfunction: A Pilot Resting-State Functional MRI Study

Premorbid Alterations of Spontaneous Brain Activity in Elderly Patients With Early Post-operative Cognitive Dysfunction: A Pilot Resting-State Functional MRI Study

Background: Elderly patients with pre-existing cognitive impairment are susceptible to post-operative cognitive dysfunction (POCD). In this study, we investigated whether there is pre-existing local homogeneity and functional connectivity alteration in the brain before surgery for POCD patients as c...

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Bibliographic Details
Main Authors: Xixue Zhang, Hui Li, Yating Lv, Zhenghong Zhu, Xiaoyong Shen, Qi Lu, Wei Wang, Zhaoxin Wang, Zhaoshun Jiang, Lvjun Yang, Guangwu Lin, Weidong Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Neurology
Subjects:
resting-state fMRI
pre-operative changes in brain
cognitive decline
early post-operative period
functional connectivity
regional homogeneity
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01062/full

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https://www.frontiersin.org/article/10.3389/fneur.2019.01062/full

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