A multi-omics study to characterize the transdifferentiation of human dermal fibroblasts to osteoblast-like cells
Background: Various skeletal disorders display defects in osteoblast development and function. An in vitro model can help to understand underlying disease mechanisms. Currently, access to appropriate starting material for in vitro osteoblastic studies is limited. Native osteoblasts and their progeni...
Main Authors: | Sandra Pihlström, Kirsi Määttä, Tiina Öhman, Riikka E. Mäkitie, Mira Aronen, Markku Varjosalo, Outi Mäkitie, Minna Pekkinen |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-11-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.1032026/full |
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