A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease

A novel mechanism of PHB2-mediated mitophagy participating in the development of Parkinson's disease

Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson's disease, but the regulatory mechanism remains elusive. Prohibitin-2 (PHB2) is a newly discovered autophagy receptor in the mitochondrial inner membrane, and its role in Parkinson's disease remain...

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Bibliographic Details
Main Authors: Yongjiang Zhang, Shiyi Yin, Run Song, Xiaoyi Lai, Mengmeng Shen, Jiannan Wu, Junqiang Yan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
endoplasmic reticulum; dopaminergic neuron; microtubule-associated protein 1 light chain 3; mitophagy; oxidative stress; parkin; parkinson's disease; pkr-like endoplasmic reticulum kinase; reactive oxygen species; prohibitin-2
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=8;spage=1828;epage=1834;aulast=

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=8;spage=1828;epage=1834;aulast=

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