The changes of hepatic bile acid synthesis and transport and bile acids profiles in isopsoralen-induced liver injury C57BL/6J mice

The changes of hepatic bile acid synthesis and transport and bile acids profiles in isopsoralen-induced liver injury C57BL/6J mice

Contest Isopsoralen, one of the main active and quality-control compounds in Psoralea corylifolia L. (Fabaceae), has antitumor and oestrogen-like effects. Previous studies demonstrated that isopsoralen induced hepatotoxicity and its long-term exposure led to cholestatic liver injury.Objective This s...

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Bibliographic Details
Main Authors: Wei-jie Men, Zhao-jun Meng, Qin Wang, Meng-ying Chen, Yu-xia Zhai, Hong Shi, An-hong Wang, Kun Zhou
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Target organs
metabolism
hepatotoxicity
BAs transporters
BAs spectrum
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2116057

Internet

https://www.tandfonline.com/doi/10.1080/13880209.2022.2116057

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