Nox4-SH3YL1 complex is involved in diabetic nephropathy

Nox4-SH3YL1 complex is involved in diabetic nephropathy

Summary: Nox4-derived H2O2 generation plays an important role in the pathogenesis of chronic kidney diseases (CKDs) such as diabetic nephropathy (DN). Here, we showed that SH3 domain-containing Ysc84-like 1 (SH3YL1), a Nox4 cytosolic activator, regulated DN. Streptozotocin (STZ)-induced type Ⅰ diabe...

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Bibliographic Details
Main Authors: Sae Rom Lee, Hye Eun Lee, Jung-Yeon Yoo, Eun Jung An, Soo-Jin Song, Ki-Hwan Han, Dae Ryong Cha, Yun Soo Bae
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Pathology
Molecular biology
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000890

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http://www.sciencedirect.com/science/article/pii/S2589004224000890

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