Computational analysis of binding between malarial dihydrofolate reductases and anti-folates
<p>Abstract</p> <p>Background</p> <p><it>Plasmodium falciparum </it>readily develops resistance to the anti-folates pyrimethamine and proguanil via a characteristic set of mutations in the dihydrofolate reductase (PfDHFR) gene that leads to reduced competiti...
Main Authors: | White Nicholas J, Day Nicholas PJ, Songtawee Napat, Theppabutr Sasikrit, Choowongkomon Kiattawee, Woodrow Charles J, Imwong Mallika |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-03-01
|
Series: | Malaria Journal |
Online Access: | http://www.malariajournal.com/content/9/1/65 |
Similar Items
-
Computational analysis of binding between malarial dihydrofolate reductases and anti-folates
by: Choowongkomon, K, et al.
Published: (2010) -
Computational analysis of binding between malarial dihydrofolate reductases and anti-folates.
by: Choowongkomon, K, et al.
Published: (2010) -
Accurate and sensitive detection of Plasmodium species in humans by use of the dihydrofolate reductase-thymidylate synthase linker region.
by: Tanomsing, N, et al.
Published: (2010) -
Docking of anti-malarial drug derivatives into Plasmodium Vivax dihydrofolate reductase /
by: Wong, Bing Ming, 1986-, et al.
Published: (2009) -
The binding of trimethoprim to bacterial dihydrofolate reductase.
by: Baker, D, et al.
Published: (1981)