Establishment and Characterization of NCC-DDLPS4-C1: A Novel Patient-Derived Cell Line of Dedifferentiated Liposarcoma

Establishment and Characterization of NCC-DDLPS4-C1: A Novel Patient-Derived Cell Line of Dedifferentiated Liposarcoma

Dedifferentiated liposarcoma (DDLPS) is a highly malignant sarcoma characterized by the co-amplification of <i>MDM2</i> and <i>CDK4</i>. Although systemic chemotherapy is recommended for unresectable or metastatic cases, DDLPS is insensitive to conventional chemotherapy, lead...

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Bibliographic Details
Main Authors: Ryuto Tsuchiya, Yuki Yoshimatsu, Rei Noguchi, Yooksil Sin, Takuya Ono, Taro Akiyama, Takeshi Hirose, Shintaro Iwata, Akihiko Yoshida, Seiji Ohtori, Akira Kawai, Tadashi Kondo
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Journal of Personalized Medicine
Subjects:
sarcoma
liposarcoma
dedifferentiated liposarcoma
patient-derived cell line
Online Access:https://www.mdpi.com/2075-4426/11/11/1075

Internet

https://www.mdpi.com/2075-4426/11/11/1075

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