Intrinsic resistance to ROS1 inhibition in a patient with CD74‐ROS1 mediated by AXL overexpression

Abstract Background The vast majority of patients with ROS1 positive non‐small cell lung cancer (NSCLC) derive clinical benefit from currently approved ROS1 therapies, including crizotinib and entrectinib. However, a small proportion of patients treated with ROS1 inhibitors fail to derive any clinic...

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Bibliographic Details
Main Authors: Tara L. Peters, Nan Chen, Logan C. Tyler, Anh T. Le, Anastasios Dimou, Robert C. Doebele
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Thoracic Cancer
Subjects:
Online Access:https://doi.org/10.1111/1759-7714.15116