Hsa-miR-1908-3p Mediates the Self-Renewal and Apoptosis of Human Spermatogonial Stem Cells via Targeting KLF2

Hsa-miR-1908-3p Mediates the Self-Renewal and Apoptosis of Human Spermatogonial Stem Cells via Targeting KLF2

Spermatogenesis depends on precise epigenetic and genetic regulation of spermatogonial stem cells (SSCs). However, it remains largely unknown about the roles and mechanisms of small noncoding RNA in regulating the self-renewal and apoptosis of human SSCs. Notably, we have found that Homo sapiens-mic...

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Bibliographic Details
Main Authors: Wei Chen, Yinghong Cui, Bang Liu, Chunyun Li, Li Du, Ruiling Tang, Lulu Qin, Yiqun Jiang, Jian Li, Xing Yu, Quanyuan He, Zuping He
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
hsa-miR-1908-3p
human spermatogonial stem cells
self-renewal
apoptosis
KLF2
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301244

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http://www.sciencedirect.com/science/article/pii/S2162253120301244

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