The Polyamine Analogue Ivospemin Increases Chemotherapeutic Efficacy in Murine Ovarian Cancer

Polyamines are small polycationic alkylamines that are absolutely required for the continual growth and proliferation of cancer cells. The polyamine analogue ivospemin, also known as SBP-101, has shown efficacy in slowing pancreatic and ovarian tumor progression in vitro and in vivo and has demonstr...

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Bibliographic Details
Main Authors: Cassandra E. Holbert, Jackson R. Foley, Robert A. Casero, Tracy Murray Stewart
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/12/6/1157