IN VITRO EFFECTS OF HEME ON THE ACTIVATION OF MICROVASCULAR ENDOTHELIAL CELLS, HMEC-1

Introduction: Sickle cell anemia (SCA) is a hereditary condition characterized by morphological changes in erythrocytes, which increase their fragility and susceptibility to rupture, releasing intracellular components, including the heme molecule. Release of heme during intravascular hemolysis is cl...

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Bibliographic Details
Main Authors: VF Alberto, PL Brito, FC Leonardo, EMF Gotardo, LFS Gushiken, FF Costa, N Conran
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137924004255