Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects

Hypermethylation of PI3K-AKT signalling pathway genes is associated with human neural tube defects

Neural tube defects (NTDs) are a group of common and severe congenital malformations. The PI3K-AKT signalling pathway plays a crucial role in the neural tube development. There is limited evidence concerning any possible association between aberrant methylation in PI3K-AKT signalling pathway genes a...

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Bibliographic Details
Main Authors: Tian Tian, Xinyuan Lai, Kuanhui Xiang, Xiao Han, Shengju Yin, Robert M. Cabrera, John W. Steele, Yunping Lei, Xuanye Cao, Richard H. Finnell, Linlin Wang, Aiguo Ren
Format: Article
Language:English
Published: Taylor & Francis Group 2022-02-01
Series:Epigenetics
Subjects:
neural tube defects,
pi3k-akt signalling pathway
methylation
Online Access:http://dx.doi.org/10.1080/15592294.2021.1878725

Internet

http://dx.doi.org/10.1080/15592294.2021.1878725

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