Immunization with <i>centrin</i>-Deficient <i>Leishmania braziliensis</i> Does Not Protect against Homologous Challenge

Immunization with <i>centrin</i>-Deficient <i>Leishmania braziliensis</i> Does Not Protect against Homologous Challenge

Immunization with various <i>Leishmania</i> species lacking <i>centrin</i> induces robust immunity against a homologous and heterologous virulent challenge, making <i>centrin</i> mutants a putative candidate for a leishmaniasis vaccine. Centrin is a calcium-bindin...

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Bibliographic Details
Main Authors: Francys Avendaño-Rangel, Gabriela Agra-Duarte, Pedro B. Borba, Valdomiro Moitinho, Leslye T. Avila, Larissa O. da Silva, Sayonara M. Viana, Rohit Sharma, Sreenivas Gannavaram, Hira L. Nakhasi, Camila I. de Oliveira
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Vaccines
Subjects:
live attenuated vaccine
immunization
vaccination
cutaneous leishmaniasis
Online Access:https://www.mdpi.com/2076-393X/12/3/310

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https://www.mdpi.com/2076-393X/12/3/310

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