Construction of a Recombinant Japanese Encephalitis Virus with a Hemagglutinin-Tagged NS2A: A Model for an Analysis of Biological Characteristics and Functions of NS2A during Viral Infection

Construction of a Recombinant Japanese Encephalitis Virus with a Hemagglutinin-Tagged NS2A: A Model for an Analysis of Biological Characteristics and Functions of NS2A during Viral Infection

Nonstructural protein 2A (NS2A) of the Japanese encephalitis virus (JEV) contributes to viral replication and pathogenesis; however, a lack of NS2A-specific antibodies restricts studies on the underlying mechanisms. In this study, we constructed a recombinant JEV with a hemagglutinin (HA)-tagged NS2...

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Bibliographic Details
Main Authors: Xiaochun Ma, Chenxi Li, Qiqi Xia, Yan Zhang, Yang Yang, Abdul Wahaab, Ke Liu, Zongjie Li, Beibei Li, Yafeng Qiu, Jianchao Wei, Zhiyong Ma
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Viruses
Subjects:
Japanese encephalitis virus
nonstructural protein 2A (NS2A)
HA-tag
recombinant virus
NS1’
replication
Online Access:https://www.mdpi.com/1999-4915/14/4/706

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https://www.mdpi.com/1999-4915/14/4/706

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