Involvement of the Antioxidant Effect and Anti-inflammatory Response in Butyrate-Inhibited Vascular Smooth Muscle Cell Proliferation

Involvement of the Antioxidant Effect and Anti-inflammatory Response in Butyrate-Inhibited Vascular Smooth Muscle Cell Proliferation

Epigenetic mechanisms by altering the expression and, in turn, functions of target genes have potential to modify cellular processes that are characteristics of atherosclerosis, including inflammation, proliferation, migration and apoptosis/cell death. Butyrate, a natural epigenetic modifier and a h...

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Bibliographic Details
Main Authors: Omana P. Mathew, Kasturi Ranganna, Shirlette G. Milton
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:Pharmaceuticals
Subjects:
butyrate
vascular smooth muscle cells
glutathione peroxidase
NF-κB
proliferation
inflammation
Online Access:http://www.mdpi.com/1424-8247/7/11/1008

Internet

http://www.mdpi.com/1424-8247/7/11/1008

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