Supplementation of Methyl-Donor Nutrients to a High-Fat, High-Sucrose Diet during Pregnancy and Lactation Normalizes Circulating 25-Dihydroxycholecalciferol Levels and Alleviates Inflammation in Offspring

Supplementation of Methyl-Donor Nutrients to a High-Fat, High-Sucrose Diet during Pregnancy and Lactation Normalizes Circulating 25-Dihydroxycholecalciferol Levels and Alleviates Inflammation in Offspring

A Western-style diet that is high in fat and sucrose has been shown to alter DNA methylation and epigenetically modify genes related to health risk in offspring. Here, we investigated the effect of a methyl-donor nutrient (MS) supplemented to a high-fat, high-sucrose (HFS) diet during pregnancy and...

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Bibliographic Details
Main Authors: Chin May Teoh, Analynn Cooper, Karisa M. Renteria, Michelle Lane, Jie Zhu, Gar Yee Koh
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Metabolites
Subjects:
vitamin D
obesogenic diet
methyl-donor nutrients
inflammation
maternal-fetal nutrition
epigenetic
Online Access:https://www.mdpi.com/2218-1989/12/12/1252

Internet

https://www.mdpi.com/2218-1989/12/12/1252

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