Differential susceptibility to lipopolysaccharide affects the activation of toll-like-receptor 4 signaling in THP-1 cells and PMA-differentiated THP-1 cells

Monocytes and macrophages that originate from common myeloid progenitors perform various crucial roles in the innate immune system. Stimulation with LPS combined with TLR4 drives the production of pro-inflammatory cytokines through MAPKs and NF-κB pathway in different cells. However, the difference...

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Bibliographic Details
Main Authors: Young Kyu Kim, Jeong Ho Hwang, Hoon Taek Lee
Format: Article
Language:English
Published: SAGE Publishing 2022-04-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259221100170