Differential susceptibility to lipopolysaccharide affects the activation of toll-like-receptor 4 signaling in THP-1 cells and PMA-differentiated THP-1 cells
Monocytes and macrophages that originate from common myeloid progenitors perform various crucial roles in the innate immune system. Stimulation with LPS combined with TLR4 drives the production of pro-inflammatory cytokines through MAPKs and NF-κB pathway in different cells. However, the difference...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2022-04-01
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Series: | Innate Immunity |
Online Access: | https://doi.org/10.1177/17534259221100170 |