Interleukin 4 promotes phagocytosis of murine leukemia cells counteracted by CD47 upregulation
Cytokines are key regulators of tumor immune surveillance by controlling immune cell activity. Here, we investigated whether interleukin 4 (IL4) has antileukemic activity via immune-mediated mechanisms in an in vivo murine model of acute myeloid leukemia driven by the MLL–AF9 fusion gene. Although...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2021-05-01
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| Series: | Haematologica |
| Online Access: | https://haematologica.org/article/view/10259 |