Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1

Atherosclerosis results from the deposition and oxidation of LDL and immune cell infiltration in the sub-arterial space leading to arterial occlusion. Studies have shown that transcytosis transports circulating LDL across endothelial cells lining blood vessels. LDL transcytosis is initiated by bindi...

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Bibliographic Details
Main Authors: Karen Y.Y. Fung, Tse Wing Winnie Ho, Zizhen Xu, Dante Neculai, Catherine A.A. Beauchemin, Warren L. Lee, Gregory D. Fairn
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752400035X