Protein Turnover in Epithelial Cells and Mucus along the Gastrointestinal Tract Is Coordinated by the Spatial Location and Microbiota

Summary: The gastrointestinal tract is covered by a single layer of epithelial cells that, together with the mucus layers, protect the underlying tissue from microbial invasion. The epithelium has one of the highest turnover rates in the body. Using stable isotope labeling, high-resolution mass spec...

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Bibliographic Details
Main Authors: Liisa Arike, Andrus Seiman, Sjoerd van der Post, Ana M. Rodriguez Piñeiro, Anna Ermund, André Schütte, Fredrik Bäckhed, Malin E.V. Johansson, Gunnar C. Hansson
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719317255