How do prolonged anchorage-free lifetimes strengthen non-small-cell lung cancer cells to evade anoikis? – A link with altered cellular metabolomics

How do prolonged anchorage-free lifetimes strengthen non-small-cell lung cancer cells to evade anoikis? – A link with altered cellular metabolomics

Abstract Background Malignant cells adopt anoikis resistance to survive anchorage-free stresses and initiate cancer metastasis. It is still unknown how varying periods of anchorage loss contribute to anoikis resistance, cell migration, and metabolic reprogramming of cancerous cells. Results Our stud...

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Bibliographic Details
Main Authors: Rungroch Sungthong, Hnin Ei Ei Khine, Somruethai Sumkhemthong, Pithi Chanvorachote, Rossarin Tansawat, Chatchai Chaotham
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Biological Research
Subjects:
Non-small-cell lung cancer
Anchorage-independent growth
Anoikis
Anoikis resistance
Metastasis
Metabolomics
Online Access:https://doi.org/10.1186/s40659-023-00456-z

Internet

https://doi.org/10.1186/s40659-023-00456-z

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