PEGylated aceclofenac solid lipid microparticles homolipid-based solidified reverse micellar solutions for drug delivery

Aceclofenac is a non-steroidal anti-inflammatory drug with poor aqueous solubility and a short half-life resulting in low bioavailability. Aceclofenac-loaded solid lipid microparticles based solidified reverse micellar solution (SLMs-SRMS) for oral drug delivery was investigated to improve the bioav...

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Bibliographic Details
Main Authors: Calister E. Ugwu, Jude N. Oraeluno, Kingsley C. Eze, Caleb O. Ezenma, Anthony O. Nwankwo
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022005357