The delta opioid receptor agonist KNT‐127 relieves innate anxiety‐like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala

The delta opioid receptor agonist KNT‐127 relieves innate anxiety‐like behavior in mice by suppressing transmission from the prelimbic cortex to basolateral amygdala

Abstract Aim Excitatory projections from the prelimbic cortex (PL) to the basolateral nucleus of the amygdala (BLA) are implicated in the regulation of anxiety‐like behaviors, and we previously demonstrated that anxiolytic‐like effects of the selective delta‐opioid receptor (DOP) agonist KNT‐127 is...

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Bibliographic Details
Main Authors: Ayako Kawaminami, Daisuke Yamada, Toshinori Yoshioka, Azumi Hatakeyama, Moeno Nishida, Keita Kajino, Tsuyoshi Saitoh, Hiroshi Nagase, Akiyoshi Saitoh
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Neuropsychopharmacology Reports
Subjects:
anxiety
basic
basolateral amygdala
delta opioid receptor
excitatory synaptic transmission
prelimbic cortex
Online Access:https://doi.org/10.1002/npr2.12406

Internet

https://doi.org/10.1002/npr2.12406

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