Nanoparticles engineered to bind cellular motors for efficient delivery

Nanoparticles engineered to bind cellular motors for efficient delivery

Abstract Background Dynein is a cytoskeletal molecular motor protein that transports cellular cargoes along microtubules. Biomimetic synthetic peptides designed to bind dynein have been shown to acquire dynamic properties such as cell accumulation and active intra- and inter-cellular motion through...

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Bibliographic Details
Main Authors: Inmaculada Dalmau-Mena, Pablo del Pino, Beatriz Pelaz, Miguel Ángel Cuesta-Geijo, Inmaculada Galindo, María Moros, Jesús M. de la Fuente, Covadonga Alonso
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Nanobiotechnology
Subjects:
Nanoparticles
Biomimetic synthetic peptides
Drug delivery
Microtubule motors
Dynein
Online Access:http://link.springer.com/article/10.1186/s12951-018-0354-1

Internet

http://link.springer.com/article/10.1186/s12951-018-0354-1

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