The rs1051931 G>A Polymorphism in the PLA2G7 Gene Confers Resistance to Immunoglobulin Therapy in Kawasaki Disease in a Southern Chinese Population

The rs1051931 G>A Polymorphism in the PLA2G7 Gene Confers Resistance to Immunoglobulin Therapy in Kawasaki Disease in a Southern Chinese Population

Background: Kawasaki disease (KD) is a common cardiovascular disease in infants and young children, with fever, rash, and conjunctivitis as the main clinical manifestations, which can lead to the occurrence of coronary aneurysms. Intravenous immunoglobulin (IVIG) is the preferred treatment for KD pa...

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Bibliographic Details
Main Authors: Xueping Gu, Wenchun Lin, Yufen Xu, Di Che, Yaqian Tan, Zhaoliang Lu, Lei Pi, Lanyan Fu, Huazhong Zhou, Zhiyong Jiang, Xiaoqiong Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pediatrics
Subjects:
rs1051931
polymorphism
PLA2G7
immunoglobulin therapy
Kawasaki disease
Online Access:https://www.frontiersin.org/article/10.3389/fped.2020.00338/full

Internet

https://www.frontiersin.org/article/10.3389/fped.2020.00338/full

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