Shift in Tissue-Specific Immune Niches and CD137 Expression in Tuberculoma of Pembrolizumab-Treated Nasopharyngeal Carcinoma Patients

Shift in Tissue-Specific Immune Niches and CD137 Expression in Tuberculoma of Pembrolizumab-Treated Nasopharyngeal Carcinoma Patients

The use of immune checkpoint inhibitors (ICIs) in cancer treatment has shown promise but can also have unintended consequences, such as reactivating latent tuberculosis (TB). To develop treatments that address ICIs-related adverse events, it is essential to understand cellular heterogeneity across h...

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Bibliographic Details
Main Authors: Ngar Woon Kam, Anthony Wing Ip Lo, Desmond Tae Yang Hung, Ho Ko, Ka Chun Wu, Dora Lai Wan Kwong, Ka On Lam, To Wai Leung, Chi Ming Che, Victor Ho Fun Lee
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
CD137
tissue-specific immune microenvironment
immune checkpoint inhibitors
macrophages
nasopharyngeal carcinoma
spatial
Online Access:https://www.mdpi.com/2072-6694/16/2/268

Internet

https://www.mdpi.com/2072-6694/16/2/268

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