Deletions of singular U1 snRNA gene significantly interfere with transcription and 3'-end mRNA formation.

Small nuclear RNAs (snRNAs) are structural and functional cores of the spliceosome. In metazoan genomes, each snRNA has multiple copies/variants, up to hundreds in mammals. However, the expressions and functions of each copy/variant in one organism have not been systematically studied. Focus on U1 s...

Full description

Bibliographic Details
Main Authors: Mei Wang, An-Min Liang, Zhen-Zhen Zhou, Ting-Lin Pang, Yu-Jie Fan, Yong-Zhen Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011021&type=printable