The impact of D-cycloserine and sarcosine on in vivo frontal neural activity in a schizophrenia-like model

The impact of D-cycloserine and sarcosine on in vivo frontal neural activity in a schizophrenia-like model

Abstract Background N-methyl-D-aspartate receptor (NMDAR) hypofunction has been proposed to underlie the pathogenesis of schizophrenia. Specifically, reduced function of NMDARs leads to altered balance between excitation and inhibition which further drives neural network malfunctions. Clinical studi...

Full description

Bibliographic Details
Main Authors: Lulu Yao, Zongliang Wang, Di Deng, Rongzhen Yan, Jun Ju, Qiang Zhou
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Psychiatry
Subjects:
NMDARs
Schizophrenia
NMDAR co-agonist
Calcium imaging
Single unit recording
Online Access:http://link.springer.com/article/10.1186/s12888-019-2306-1

Internet

http://link.springer.com/article/10.1186/s12888-019-2306-1

Similar Items