The effect of continuous intravenous norepinephrine infusion on systemic hemodynamics in a telemetrically-monitored mouse model of sepsis.

Sepsis, a life-threatening organ dysfunction, results from dysregulated host responses to infection and still has a high incidence and mortality. Although administration of vasopressors to treat septic shock is standard of care, the benefits are not well established. We evaluated the effect of conti...

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Bibliographic Details
Main Authors: Tetsushi Yamashita, Jonathan M Street, Brianna C Halasa, Yoshitaka Naito, Takayuki Tsuji, Naoko Tsuji, Naoki Hayase, Peter S T Yuen, Robert A Star
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0271667