LAMC1 upregulation via TGFβ induces inflammatory cancer‐associated fibroblasts in esophageal squamous cell carcinoma via NF‐κB–CXCL1–STAT3

LAMC1 upregulation via TGFβ induces inflammatory cancer‐associated fibroblasts in esophageal squamous cell carcinoma via NF‐κB–CXCL1–STAT3

Cancer‐associated fibroblasts (CAF) are a heterogeneous cell population within the tumor microenvironment,and play an important role in tumor development. By regulating the heterogeneity of CAF, transforming growth factor β (TGFβ) influences tumor development. Here, we explored oncogenes regulated b...

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Bibliographic Details
Main Authors: Lingling Fang, Yun Che, Chaoqi Zhang, Jianbing Huang, Yuanyuan Lei, Zhiliang Lu, Nan Sun, Jie He
Format: Article
Language:English
Published: Wiley 2021-11-01
Series:Molecular Oncology
Subjects:
CAF
CXCL1
ESCC
heterogeneity
LAMC1
transforming growth factor β
Online Access:https://doi.org/10.1002/1878-0261.13053

Internet

https://doi.org/10.1002/1878-0261.13053

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