Association among insulin receptor substrate1 genetic polymorphism, sulfonylurea therapeutic efficacy, and insulin resistance in patients with type 2 diabetes mellitus
Background Insulin receptor substrate-1 gene (IRS-1) is an endogenous substrate of the insulin receptor present in insulin-sensitive tissues, allowing insulin signaling to take place. The IRS-1, rs1801278 gene with Gly972Arg substitution polymorphism is one of the most commonly studied variants in r...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
General Organization of Teaching Hospitals and Institutes
2021-01-01
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| Series: | Journal of Medicine in Scientific Research |
| Subjects: | |
| Online Access: | http://www.jmsr.eg.net/article.asp?issn=2537-091X;year=2021;volume=4;issue=3;spage=196;epage=201;aulast=Omar |