The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors

The Neurokinin-1 Receptor Is a Target in Pediatric Rhabdoid Tumors

Rhabdoid tumors (RT) are among the most aggressive tumors in early childhood. Overall survival remains poor, and treatment only effectively occurs at the cost of high toxicity and late adverse effects. It has been reported that the neurokinin-1 receptor/ substance P complex plays an important role i...

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Bibliographic Details
Main Authors: Julian Kolorz, Salih Demir, Adrian Gottschlich, Iris Beirith, Matthias Ilmer, Daniel Lüthy, Christoph Walz, Mario M. Dorostkar, Thomas Magg, Fabian Hauck, Dietrich von Schweinitz, Sebastian Kobold, Roland Kappler, Michael Berger
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Current Oncology
Subjects:
rhabdoid tumor
NK-1 receptor
NK-1 receptor antagonist
substance P
cancer
apoptosis
Online Access:https://www.mdpi.com/1718-7729/29/1/8

Internet

https://www.mdpi.com/1718-7729/29/1/8

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