Use of metolazone as an adjunct therapy to loop diuretics in diuretic resistant acute decompensation of heart failure: A systematic review and meta-analysis

Introduction: Loop diuretics are the first-line treatment for volume overload in acute decompensation of congestive heart failure (AHF). Loop diuretic resistance is common due to pharmacologic tachyphylaxis. Therefore, thiazide and thiazide-like diuretics are often used as add-on therapy to combine...

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Main Authors: Dhan Bahadur Shrestha, Yub Raj Sedhai, Suman Gaire, Barun Babu Aryal, Karan Singh, Irfan Waheed, Wasey Ali Yadullahi Mir, Mohammad Saud Khan, Jacquelene Dawson Dowe, Mohammed Kazimuddin, Soney Basnyat, Ankush Asija, Nimesh K. Patel
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Health Sciences Review
Online Access:http://www.sciencedirect.com/science/article/pii/S277263202300020X