Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies

Introduction: Skeletal muscle is a major contributor to whole-body energy homeostasis and the utilization of fatty acids and glucose. At present, 2D cell models have been the most used cellular models to study skeletal muscle energy metabolism. However, the transferability of the results to in vivo...

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Bibliographic Details
Main Authors: Andrea Dalmao-Fernandez, Aleksandra Aizenshtadt, Hege G. Bakke, Stefan Krauss, Arild C. Rustan, G. Hege Thoresen, Eili Tranheim Kase
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1130693/full