Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury

Argon reduces microglial activation and inflammatory cytokine expression in retinal ischemia/reperfusion injury

We previously found that argon exerts its neuroprotective effect in part by inhibition of the toll-like receptors (TLR) 2 and 4. The downstream transcription factors signal transducer and activator of transcription 3 (STAT3) and nuclear factor kappa B (NF-κB) are also affected by argon and may play...

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Bibliographic Details
Main Authors: Ulrich Goebel, Stefanie Scheid, Sashko Spassov, Nils Schallner, Jakob Wollborn, Hartmut Buerkle, Felix Ulbrich
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
argon; ischemia/reperfusion injury; microglia; neuroinflammation; neuroprotection; noble gas; sh-sy5y; toll-like receptor; transcription factor
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=1;spage=192;epage=198;aulast=Goebel

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=1;spage=192;epage=198;aulast=Goebel

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