Utility of circulating tumour DNA for prognosis and prediction of therapeutic effect in locally recurrent rectal cancer: study protocol for a multi-institutional, prospective observational study (JCOG1801A1, CAP-LR study)

Introduction In locally recurrent rectal cancer (LRRC), surgery is a standard treatment for resectable disease. However, short-term and long-term outcomes are unsatisfactory due to the invasive nature of surgical procedures and the high proportion of local recurrence. Consequently, the identificatio...

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Main Authors: Atsuo Takashima, Masaaki Ito, Yukihide Kanemitsu, Tadayoshi Hashimoto, Yuichiro Tsukada, Keisuke Kanato, Junki Mizusawa, Haruhiko Fukuda, Shunsuke Tsukamoto
Format: Article
Language:English
Published: BMJ Publishing Group 2023-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/8/e073217.full