Light-switchable transcription factors obtained by direct screening in mammalian cells

Abstract Optogenetic tools can provide fine spatial and temporal control over many biological processes. Yet the development of new light-switchable protein variants remains challenging, and the field still lacks general approaches to engineering or discovering protein variants with light-switchable...

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Dettagli Bibliografici
Autori principali: Liyuan Zhu, Harold M. McNamara, Jared E. Toettcher
Natura: Articolo
Lingua:English
Pubblicazione: Nature Portfolio 2023-06-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-023-38993-6

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