Light-switchable transcription factors obtained by direct screening in mammalian cells
Abstract Optogenetic tools can provide fine spatial and temporal control over many biological processes. Yet the development of new light-switchable protein variants remains challenging, and the field still lacks general approaches to engineering or discovering protein variants with light-switchable...
Autori principali: | Liyuan Zhu, Harold M. McNamara, Jared E. Toettcher |
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Natura: | Articolo |
Lingua: | English |
Pubblicazione: |
Nature Portfolio
2023-06-01
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Serie: | Nature Communications |
Accesso online: | https://doi.org/10.1038/s41467-023-38993-6 |
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