Light-switchable transcription factors obtained by direct screening in mammalian cells
Abstract Optogenetic tools can provide fine spatial and temporal control over many biological processes. Yet the development of new light-switchable protein variants remains challenging, and the field still lacks general approaches to engineering or discovering protein variants with light-switchable...
| Auteurs principaux: | , , |
|---|---|
| Format: | Article |
| Langue: | English |
| Publié: |
Nature Portfolio
2023-06-01
|
| Collection: | Nature Communications |
| Accès en ligne: | https://doi.org/10.1038/s41467-023-38993-6 |