The role of angiotensin receptor blocker (losartan) on decreasing fibrotic process of corpora cavernosa in priapism model of wistar rats [version 3; peer review: 1 approved, 2 approved with reservations]
Background Priapism induces regulation of Transforming Growth Factor-β1 (TGF-β1) expression and collagen-type-1 deposition. This will replace the normal corpora cavernosa with fibrotic tissue which eventually resulted in erectile dysfunction. It is also known that the fibrosis process of corpora cav...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2024-02-01
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Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/11-831/v3 |