Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet

Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet

A key objective of this study was to explore the potential of dietary grape consumption to modulate adverse effects caused by a high-fat (western-pattern) diet. Female C57BL/6J mice were purchased at six-weeks-of-age and placed on a standard (semi-synthetic) diet (STD). At 11 weeks-of-age, the mice...

Full description

Bibliographic Details
Main Authors: Asim Dave, Eun-Jung Park, Avinash Kumar, Falguni Parande, Diren Beyoğlu, Jeffrey R. Idle, John M. Pezzuto
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Foods
Subjects:
grapes
metabolic diseases
C57BL/6J mice
high-fat diet
RNA sequencing
nutrigenomics
Online Access:https://www.mdpi.com/2304-8158/11/13/1984

Internet

https://www.mdpi.com/2304-8158/11/13/1984

Similar Items